AIC Bioinformatics Toolbox 
Chinese
We are excited to introduce you to the comprehensive suite of tools developed by AIC LLC, designed to enhance your data analysis and research capabilities. Whether you're looking to get quick answers, perform in-depth searches, check your grammar, rephrase your text, translate your texts to English or Chinese, or explore complex interactions, our tools have got you covered. Dive into our range of services to streamline your workflow and achieve your goals with ease. Below, you'll find detailed descriptions of each tool and how they can assist you in your work.
Search Tools
- Type your question in the left box and click the "AIC ask" button to get answers.
- Enter Entity1, Entity2, Key Question, and Highlights in the left box and click the "Search" button to retrieve relevant results. Subscribers can download associated data files. Please see the examples 1~4 for the input format.
- Discover the shortest path between two entities by entering Entity1, Entity2, Key Question, and Highlights in the left box and clicking the "Shortest Path" button. Subscribers can download associated data files. Please see the examples 1 and 2 for the input format.
Note: This tool is designed for two major research applications: 1) exploring connections between two items that have no previously reported direct association (e.g., hypothesis testing or supporting novel findings); and 2) investigating the mechanisms between two items that have a known association.
Writing Tools
- Get your English grammar checked by pasting your text in the left box and clicking the "Grammar Check" button.
- Find different and better ways to express your ideas by entering your English text in the left box and clicking the "Rephrase" button.
- Check for possible spelling and grammatical errors and rewrite as necessary.
- Translate English to Chinese or Chinese to English by entering the text in the left box and clicking the corresponding "To Chinese" or "To English" button.
Other Tools
- Under ‘Other tools’, this module analyzes protein-protein interactions (PPI) by entering multiple genes in the left box, selecting either ‘LDM’ or ‘String’, and clicking the "PPI" button. Subscribers can download associated data files. To note, 'LDM' refers to building literature data mining-based PPIs, while 'String' refers to building STRING database-based PPIs.
- Under ‘Other tools’, this module maps genetic variants to their corresponding gene(s) by entering the genetic variant IDs in the left box and clicking the 'SNP2Gene' button.
- Under ‘Other tools’, this is a recommended free tool for Venn plot for up to four lists. Copy rights belongs to Juan Carlos Oliveros.
- Under ‘Other tools’, this is an advanced function for batch processing. It is designed for VIP user only.
Registration and Subscription
To use the AIC tool package, you need to register by selecting the 'Sign up' option at the top of the main page. A confirmation email will be sent to the provided email address, containing a confirmation link. Clicking this link will activate your account. Once your account is activated, you can sign in and access all the tools. Unsubscribed users can make up to 10 free queries each day, while subscribed users enjoy unlimited access and data file downloading.
To gain unlimited access to the AIC tool package with the capability to download data files, you need to subscribe by selecting one of the subscription options below. Please note that the unit price is $1 per day.
Weekly Essential Access - $5.00 (28% discount)
Monthly Pro Access - $18.00 (40% discount)
Six-Month Premium Access - $90.00 (50% discount)
One-Year Elite Access - $160.00 (56% discount)
Exclusive VIP Access - Contact AIC for details
Note: 1) You can make a payment using PayPal or with credit or debit cards. 2) As a VIP user, besides unlimited access to online tool packages and data downloading capabilities, you can also perform batch processing and submit specific requirements for customized solutions.
FAQs
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Answer: The AIC Bioinformatics Toolbox (ABT) is crafted with the primary aim of swiftly addressing inquiries and conducting comprehensive searches pertaining to biology, bioinformatics, and biomedical fields, complete with supported references.
Furthermore, it aids in scientific report drafting and manuscript composition by offering grammar checks, paraphrasing assistance, and translation services. Additionally, ABT furnishes tools commonly employed in biological research, such as SNP-to-Gene mapping, PPI analysis, and Venn plot generation.
In summary, ABT platform is designed for:
1) Obtain answers to a general biology/bioinformatics question without references (AIC ask).
2) Receive summarized answer to a biology/bioinformatics query with references (AIC search).
3) Explore potential connections between two items without known association (Shortest Path)
4) Investigate the mechanisms underlying connections between two items with established associations (Shortest Path)
5) Conduct grammar checks on input text in any language (Grammar Check).
6) Enhance writing quality (Rephrase).
7) Translate text from any language to English or Chinese (Translate).
8) Analyze protein-protein interactions (PPI).
9) Perform SNP to gene mapping (SNP2Gen).
10) Generate Venn plots (VENN).
11) Execute batch processing of the aforementioned functions (Batch process).
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Answer: The AIC bioinformatics toolbox (ABT) draws its data from the AIC bioinformatics database (ABD), which offers a comprehensive array of information spanning various domains within biology, bioinformatics, and the biomedical sciences. These encompass, among others:
1) Scholarly Literature: Drawn from databases like PubMed, arXiv, and bioRxiv.
2) Online Databases and Repositories: Including but not limited to GEO, Psychiatric Genomics Consortium (PGC), GenBank, the Protein Data Bank (PDB), and Ensembl.
3) Government and Organizational Reports: Accessible documents and publications from esteemed entities such as the World Health Organization (WHO), the National Institutes of Health (NIH), and the Centers for Disease Control and Prevention (CDC).
4) Scientific News Coverage: Articles and updates sourced from reputable scientific news platforms and journals like Nature News, Science Daily, and New Scientist.
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Answer: The AIC bioinformatics toolbox (ABT) employs artificial intelligence (AI)-powered natural language processing methods to extract and analyze data from ABD. It also fetches real-time data from online sources, facilitating the generation of responses to queries. Therefore, ABT serves as an AI-driven tool.
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Answer: The AIC bioinformatics database (ABD) undergoes daily updates. Whenever a query is made from the ABT, information is extracted not only from ADB but also from live online sources in real-time. Additionally, search outcomes contribute to the ongoing growth of the ABD, ensuring that it remains up-to-date over time.
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Answer: Those seeking unlimited access to the tool along with the ability to download supporting original data files.
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Answer: Because the original data file encompasses information about the data sources utilized to produce the answer, comprising reference details and relationship information. This enables inspection and facilitates accurate information citation.
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Answer: For most tools, you receive answers within seconds. However, there are two cases that may take longer:
1) For 'AIC search', if the answer is not in the database, it can take 30 to 90 seconds, depending on the inputs (e.g., using inputs from Example 3 will take longer than those from Example 1).
2) For 'Shortest Path', if the answer is not in the database, it can take up to 10 minutes.
3) For ‘PPI’ using LDM, it takes about 6 minutes.
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Answer: VIP users are those who have subscribed to a paid service or project costing $1000 or more with the AIC service team. As a VIP user, you not only have unlimited full access to the AIC Bioinformatics Toolbox (ABT), but also enjoy advanced services such as access to the AIC Experiment Database (AED), batch processing, and modeling tailored to specific requirements.